HALLO
Searching Literature and identifying evidence
Learning objectives
- - Explain publication bias.
- - Name different digital information sources and amount and levels of evidence.
- - Prepare search strategies for digital databases based on formulated clinical scenarios.
- - Manage PubMed searching and the concept of MESH terms and Boolean functions.
- - Locate best scientific evidence in PubMed & Cochrane Library.
"PhD Student1: “You know, studies with positive results are more likely to be accepted for publication than studies with negative results. Shouldn’t we take that into account when submitting our paper?” PhD Student2: “Waaaw, I didn’t know that. Moreover, my teacher always told me that negative results are also results. We are misleading the readers. And what about fraude?”
What is publication bias?
Dental materials and more specifically implant industry is evolving at high speed. Choosing the right implant component is not easy as so many different designs for specific situations have been launched.
Is there evidence the the concical-shaped implant design is preferred above the traditional butt joint design? What is the impact for the patient? Will the gums around the implant heal in a different way on the long term? How can I formulate the research question correctly?
How can I formulate the research question correctly?
What are different digital information sources and levels of evidence?
How do I need to define my literature search?
Where can I find the best evidence?
Relevant online resources:Recommended online resources on Publication bias: https://en.wikipedia.org/wiki/Publication_bias http://www.bmj.com/content/344/bmj.d7762 http://www.sciencedirect.com/science/article/pii/014067369190201Y http://www.ncbi.nlm.nih.gov/pubmed/20516298 Recommended online resources on sources of digital information and levels of evidence: www.nature.com/ebd/ www.medicine.ox.ac.uk/bandolier/ www.ncbi.nlm.nih.gov/pubmed www.ncbi.nlm.nih.gov/pubmed/clinical/ www.cebm.net http://ebd.ada.org/en/resources/ http://www.ncbi.nlm.nih.gov/pubmedhealth/finding-systematic-reviews/ http://www.ovid.com/site/catalog/databases/index.jsp The Evidence Locator provides resources of evidence-based dentistry information http://www.ncbi.nlm.nih.gov/pubmed/18783754 Evidence-based dentistry: Challenges for education and dental research. Information missing from databases and access problems http://www.jokstad.no/ Recommended online resources on search strategies for digital databases based on formulated clinical scenarios: 1.http://www.cebd.org/practising-ebd/question/ http://www.cebm.net/asking-focused-questions
1.https://www.nlm.nih.gov/bsd/disted/pubmedtutorial/cover.html 2.https://www.nlm.nih.gov/bsd/disted/pubmedtutorial/020_490.html 3.https://www.nlm.nih.gov/bsd/disted/pubmedtutorial/020_340.html 4.http://www.cebd.org/teaching-3/ EBD Workshop -Collecting the Evidence EBD Lecture- EBD a global revolution? EBD Lecture – Getting evidence into practice
1.In PubMed www.ncbi.nlm.nih.gov/pubmed/clinical/ 2.In Cochrane Library http://www.thecochranelibrary.com and http://www.cochranelibrary.com/topic/Dentistry%20%26%20oral%20health/ The Cochrane Database of Systematic Reviews Database of Abstracts of Reviews of Effects (DARE) The Cochrane Central Register of Controlled Trials (CENTRAL) The Cochrane Database of Methodology Reviews The Cochrane Methodology Register Health Technology Assessment Database (HTA) NHS Economic Evaluation Database (NHS EED) |
Optional texts local/national sites:Local ebm resources |