Knowledge and skills required to carry out critical appraisal of scientific evidence

General knowledge

Appraising Literature & Study Methodology

Biostatistics

Formulating Information Needs

Searching Literature and identifying evidence

Knowledge and skills for judging evidence of scientific research reports

Studies on interventions (therapy and prevention)

Diagnosis and Screening

Prognosis

Causation, Etiology & Harm

Systematic Reviews & Meta-analyses

Clinical Guidelines